Psoriasis The Genetic And Immune Mediated Implications

Psoriasis: The Genetic and Immune-Mediated Implications Psoriasis is a common chronic autoimmune disorder that is characterized as having an immune-mediated inflammatory pathology which presents with skin lesions that vary in severity. Affecting nearly 3% of the world population (Jadali Eslami 2014) the cause of psoriasis in not fully understood, but there is considerable evidence that points to genetic, environmental, and immunological factors that influence the disease. Psoriasis is largely associated as a skin disorder that presents with lesions that form raised, red, scaly patches which can be very uncomfortable to an affected individual. The effects of this disease primarily target the skin tissues but can disturb many other organ systems as well, resulting in negative implications affecting the health of an individual system wide. Psoriasis has even been linked with increased risks of other common illnesses including certain cancers, heart disease, as well as other immune disorders like Crohn’s disease and ulcerati ve colitis (Menter et al. 2008). Psoriasis is non-contagious and is thought to have a largely genetic component that is triggered by environmental factors such as stress or allergens. The result of these triggers is an overproduction of new skin cells, which build up to form raised silvery patches called plaques. There is no cure for psoriasis, therefore treatments focus on the relief and control of symptoms. A number ofShow MoreRelatedEssay On Implication Of JK-STAT1490 Words   |  6 PagesImplications of JAK-STAT in disease So far, we have seen that this pathway is accountable for the transduction of extracellular stimulus into transcriptional factors that regulate several cellular functions. STATs are also known to exert additional functions such as affecting oxidative phosphorylation in mitochondria, regulating chromatin compliance and epigenetic markings in the nucleus and interacting with the microtubule components in the cytoplasm which are responsible for cellular motility (4)Read MoreCase Study on Hypokalemia8797 Words   |  36 Pagesexplanation and diagram. 9. To discuss the ideal and actual medical management for the subject. 10. To interpret the diagnostic and laboratory test result and its corresponding nursing clinical implications. 11. To discuss the different medication given and its corresponding nursing responsibilities 12. To discuss implication of different nursing theorist. 13. To formulate effective nursing care plan based on actual and potential health needs. 14. To give out recommendation and health teaching applicable toRead MoreSocm Study Guide Essay30404 Words   |  122 Pagesmovement; transport; buffers; defense; control and coordination of activities | Nucleic acids | C, H, O, N, and P; nucleotides composed of phosphates, sugars, and nitrogenous bases | Obtained in diet or manufactured | Storage and processing of genetic information | High-energy compounds | Nucleotides joined to phosphates by high-energy bonds | Synthesized by all cells | Storage or transfer of energy | 10 Describe the role of enzymes in the metabolism - Enzymes are special proteins that